IDENTIFY™ Cardiology

At LabSolutions we like to get to the heart of the matter. With our Comprehensive Cardiology Panel, we analyze 122 genes that have been associated with inherited cardiology disorders such as arrhythmia disorders (irregular heart rhythm) and cardiomyopathy (disease of the heart muscle).

Our aim is to provide patients with information about future cardiac-related risks related to underlying inherited cardiac disorders. Any information gained in this panel can be used to give a better understanding of each individual’s cardiac health. It will also allow the physician and patient to develop a medical management plan to help reduce or prevent adverse cardiac-related events.

Genetic testing for inherited cardiac conditions is recommended by several medical societies including the American Heart Association, American College of Cardiology, and Heart Rhythm Society.

What is cardiomyopathy?

Defined as a disease of the heart muscle resulting in lower overall efficiency due to a reduced ability to pump blood or maintain a normal heart rhythm.

Incidence: Higher than
1 in 500 individuals

HCM: 1 in 500
DCM: 1 in 2500

Cardiomyopathy risk factors:

Long-term Hypertension
Coronary Artery Disease
Uncontrolled Heart Rhythm
Infection
Metabolic Disorders
Nutritional Deficiencies
Genetics

Cardiomyopathy Symptoms:

Chest Pain
Cough
Syncope
Dyspnea
Fatigue
Palpitations or Arrhythmias
Swelling in The Ankles and Feet
Heart Failure
Sudden Death

What is an arrhythmia?

Defined as causing an irregular heart rhythm caused by abnormal electrical activity.

Incidence: Up to 1 in 1000 individuals

LQTS: 1 in 2000
Brugada: 5 in 10000
CPVT: 1 in 2000

Arrhythmia Risk Factors

Heart Disease
High Blood Pressure
Stress
Caffeine
Smoking
Alcohol Use
Certain Medications
Genetics

Arrhythmia Symptoms

Palpitations
Slow or Irregular Heart Beat
Dizziness
Near-Syncope or Syncope
Chest Pain
Sudden Death

Who is appropriate for IDENTIFY™ testing?

A personal or familial history of the following:

  • Cardiomyopathy or an enlarged heart
  • Unexplained arrhythmia
  • Sudden and unexplained cardiac arrest
  • Implantable Cardioverter Defibrillator (ICD) or Pacemaker placement at younger than age 50
  • Sudden Infant Death Syndrome (SIDS)
  • Heart failure and/or transplant
  • Unexplained fainting and/or fainting after exercise or emotional distress

Benefits

Testing can provide patients a better understanding of potential future cardiac risks, and suggest action through tailored and proactive medical management plans. Other benefits of genetic testing may include:

  • Establish or confirm a specific diagnosis
  • Provide an explanation for the underlying cause of a heart condition
  • Uncover potential risk of developing an underlying, multisystem condition that affects more than just the heart.
  • Make informed medical decisions and provide opportunity to implement lifestyle changes
  • Identify other at-risk relatives
  • Make more informed family planning decisions

Find out more about the IDENTIFY™ test here: