IDENTIFY™ Cardiology

The IDENTIFY™ Comprehensive Cardiology Panel analyzes 122 genes that have been associated with inherited cardiology disorders, including cardiomyopathies and arrhythmia disorders.

With IDENTIFY™, we aim to provide patients with information about future cardiac-related risks related to underlying inherited cardiac disorders. Information uncovered in this panel can be used to better understand future risks and make medical management decisions to help reduce or prevent adverse cardiac-related events.

Genetic testing for inherited cardiac conditions is recommended by several medical societies including the American Heart Association, American College of Cardiology, and Heart Rhythm Society.

What is cardiomyopathy?

Defined as a disease of the heart muscle resulting in lower overall efficiency due to a reduced ability to pump blood or maintain a normal heart rhythm.

Incidence: Higher than
1 in 500 individuals

HCM: 1 in 500
DCM: 1 in 2500

Cardiomyopathy risk factors:

Long-term Hypertension
Coronary Artery Disease
Uncontrolled Heart Rhythm
Infection
Metabolic Disorders
Nutritional Deficiencies
Genetics

Cardiomyopathy Symptoms:

Chest Pain
Cough
Syncope
Dyspnea
Fatigue
Palpitations or Arrhythmias
Swelling in The Ankles and Feet
Heart Failure
Sudden Death

What is an arrhythmia?

Defined as causing an irregular heart rhythm caused by abnormal electrical activity.

Incidence: Up to 1 in 1000 individuals

LQTS: 1 in 2000
Brugada: 5 in 10000
CPVT: 1 in 2000

Arrhythmia Risk Factors

Heart Disease
High Blood Pressure
Stress
Caffeine
Smoking
Alcohol Use
Certain Medications
Genetics

Arrhythmia Symptoms

Palpitations
Slow or Irregular Heart Beat
Dizziness
Near-Syncope or Syncope
Chest Pain
Sudden Death

A personal or family history of any of the following might be appropriate for testing:

  • Unexplained arrhythmia
  • Cardiomyopathy or enlarged heart
  • Sudden and unexplained cardiac arrest
  • Unexplained syncope and/or syncope with exercise or emotional distress
  • Implantable Cardioverter Defibrillator (ICD) or Pacemaker placement at <50 years of age
  • Sudden infant death syndrome (SIDS)
  • Heart failure and/or transplant
  • A family member with one of the above conditions whose genetic cause is already known

Benefits

Testing can provide patients better understand potential future cardiac risks, and take action through tailored and proactive medical management plans. Other benefits of genetic testing may include:

  • Establish or confirm a specific diagnosis
  • Provide an explanation of the underlying cause of your heart condition
  • Uncover potential risk of developing an underlying, multisystem condition that affects more than your heart
  • Make informed medical decisions and provide an opportunity to start risk reduction strategies
  • Identify other at-risk relatives for whom genetic testing is recommended
  • Make informed family planning decisions

Find out more about the IDENTIFY™ test here: